MMP14 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14218

Overview

Synonyms Matrix metallopeptidase 14 (membrane inserted),Matrix metalloproteinase 14,Matrix metalloproteinase-14,Membrane type 1 matrix metalloproteinase,Membrane type 1 metalloprotease,Membrane type matrix metalloproteinase 1,Membrane-type matrix metalloproteinase 1,Membrane-type-1 matrix metalloproteinase,MMP 14,MMP X1,MMP-14,MMP-X1,Mmp14,MMP14,MMPX1,MT MMP 1,MT-MMP 1,MT1 MMP,MT1-MMP,MT1MMP,MTMMP 1,MTMMP1
Swissprot P50281
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human MMP14
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

 

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