MT-ND3 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16623

Overview

Synonyms EC=1.6.5.3,Mitochondrially encoded NADH dehydrogenase 3,MT-ND3,MTND3,NADH dehydrogenase subunit 3,NADH dehydrogenase,subunit 3 (complex I),NADH-ubiquinone oxidoreductase chain 3,ND3,NU3M
Swissprot P03897
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human MT-ND3
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.

 

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