MYH7 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10478

Overview

Synonyms Beta myosin heavy chain,cardiac muscle beta isoform,CMD1S,CMH1,MPD1,MYH7,MYH7,Myhc slow,MyHC-beta,MyHC-slow,MYHCB,Myopathy,distal 1,Myosin heavy chain (AA 1-96),Myosin heavy chain 7,Myosin heavy chain,Myosin heavy chain slow isoform,Myosin heavy chain,cardiac muscle beta isoform,Myosin,heavy chain 7,cardiac muscle,beta,Myosin,heavy polypeptide 7,cardiac muscle,beta,Myosin-7,Rhabdomyosarcoma antigen MU RMS 40.7A,SPMD,SPMM
Swissprot P12883
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human MYH7
Application IHC,ELISA
Recommended dilution IHC 1:10-1:50
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

 

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