MYO7A Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16626

Overview

Synonyms Deafness autosomal dominant 11,Deafness autosomal recessive 2,DFNA11,DFNB 2,DFNB2,Myo7a,Myosin 7a,Myosin VIIA (Usher syndrome 1B (autosomal recessive,severe)),Myosin VIIa,Myosin,unconventional,family VII,member A,MYOVIIA,MYU7A,NSRD 2,NSRD2,Unconventional myosin VIIa,Ush 1B,Ush1b,Usher syndrome 1B
Swissprot Q13402
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human MYO7A
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.6mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. 

 

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