MYOC Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60358

Overview

Synonyms GLC1A,GPOA,JOAG,JOAG1,Mutated trabecular meshwork-induced glucocorticoid response protein,MYOC,MYOC,Myocilin,Myocilin,trabecular meshwork inducible glucocorticoid,TIGR,Trabecular meshwork induced glucocorticoid response protein,Trabecular meshwork-induced glucocorticoid response protein
Swissprot Q99972
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human MYOC
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

 

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