NAE1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14592

Overview

Synonyms 59 kDa,A 116A10.1,Amyloid beta precursor protein binding protein 1 59kD,Amyloid beta precursor protein binding protein 1 59kDa,Amyloid beta precursor protein binding protein 1,Amyloid beta precursor protein binding protein 1,59 kDa,Amyloid beta precursor protein-binding protein 1,Amyloid protein binding protein 1,Amyloid protein-binding protein 1,APP BP1,APP-BP1,APPBP 1,APPBP1,HPP 1,HPP1,NAE 1,NAE1,NEDD8 activating enzyme E1 regulatory subunit,NEDD8 activating enzyme E1 subunit 1,NEDD8 activating enzyme E1 subunit,NEDD8-activating enzyme E1 regulatory subunit,Proto oncogene protein 1,Proto-oncogene protein 1,Protooncogene protein 1,ula 1,ULA1
Swissprot Q13564
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human NAE1
Application WB,ELISA
Recommended dilution WB 1:200-1:1000
Concentration 0.1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

 

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