Native Immunoglobulin G3 (IgG3) - Human

by USCNK
Rs. 14,300.00
SKU

Catalog no : RS01P0249

Application : SDS-PAGE; WB; ELISA; IP.

Organism : Human

Purity : > 95%

Host : Human

Expression System : Human

Mol. Mass : n/a

Chemical Formula : n/a

Assembled by : Uscn Life Science Inc.Wuhan

Formulation : Supplied as lyophilized form in 50mM TRIS, 200mM NaCl

Usage : Reconstitute in sterile PBS, pH7.2-pH7.4.

Relevance : There are four immunoglobulin G subclasses, each numbered for their relative abundance in the body. These molecules are an important part of the immune system. All immunoglobulin G molecules are made up of four chains of amino acids, connected at a central hinge in such a way that three ends extend from the center. The hinge within the immunoglobulin G3 antibody is by far the longest in all the immunoglobulin G subclasses. The length of the hinge allows immunoglobulin G3 to quickly and effectively bind to and eliminate antigens. On the other hand, the length of the hinge also makes this subclass of immunoglobulin G the most susceptible to damage from other molecules.

Storage and Stability :

  • Storage : Avoid repeated freeze/thaw cycles. Store at 2-8oC for one month. Aliquot and store at -80oC for 12 months.
  • Stability Test : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

About the Marker (complimentary) :

  • Effective Size Range : 10kDa to 70kDa.
  • Protein bands : 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
  • Double intensity bands : The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
  • Ready-to-use : No need to heat, dilute or add reducing agents before use.

 

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