NEK10 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-13023

Overview

Synonyms FLJ32685,Never in mitosis A related kinase 10,NIMA (never in mitosis gene a) related kinase 10,NimA related protein kinase 10,Serine/threonine protein kinase Nek10
Swissprot Q6ZWH5
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human NEK10
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Nek10 (NIMA (never in mitosis gene a)-related kinase 10) is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.

 

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