NLRP12 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-13436


Synonyms CLR19.3,FCAS2,Monarch 1,Monarch-1,NACHT,leucine rich repeat and PYD containing 12,NACHT,LRR and PYD containing protein 12,NACHT,LRR and PYD domains-containing protein 12,NAL12,NLR family,pyrin domain containing 12,NLRP12,Nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 12,OTTHUMP00000067227,PAN6,PYPAF7,PYRIN containing APAF1 like protein 7,PYRIN-containing APAF1-like protein 7,Regulated by nitric oxide,RNO,RNO2
Swissprot P59046
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human NLRP12
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.6mg/mL
Clonality Polyclonal


Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.


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