NME7 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10492

Overview

Synonyms MN23H7,NDK 7,NDK7,NDP kinase 7,nm23 H7,nm23-H7,NME/NM23 family member 7,Nme7,Non metastatic cells 7 protein expressed in (nucleoside diphosphate kinase),Nucleoside diphosphate kinase 7
Swissprot Q9Y5B8
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human NME7
Application WB,ELISA
Recommended dilution WB 1:200-1:1000
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background nm23-H7, also known as NME7 (non-metastatic cells 7), is a 376 amino acid protein that contains one DM10 domain and belongs to the NDK family. Using magnesium as a cofactor, nm23-H7 functions to catalyze the ATP-dependent creation of nucleoside triphosphates, thereby playing an essential role in metabolic pathways throughout the body. The gene encoding nm23-H7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

 

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