NTRK2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-70156

Overview

Synonyms AI848316,BDNF tropomyosine receptor kinase B,BDNF/NT 3 growth factors receptor,BDNF/NT-3 growth factors receptor,Brain derived neurotrophic factor receptor,C030027L06Rik,EC 2.7.10.1,GP145 TrkB,GP145-TrkB,GP145-TrkB/GP95-TrkB,GP95 TrkB,Neurotrophic receptor tyrosine kinase 2,Neurotrophic tyrosine kinase receptor type 2,Neurotrophin receptor tyrosine kinase type 2,NTRK 2,Ntrk2,NTRK2,Obesity,hyperphagia,and developmental delay,included,RATTRKB1,Tkrb,Trk B,Trk-B,TRKB,TrkB tyrosine kinase,TRKB1,Tropomyosin related kinase B,tyrosine kinase receptor B,Tyrosine receptor kinase B
Swissprot P15209,Q63604
Source Rabbit
Reactivity Mouse,Rat
Immunogen Recombinant protein corresponding to Mouse TRKB
Application IHC
Recommended dilution IHC 1:500-1:1000
Concentration 0.6 mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
Background This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

 

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