P2RY12 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-65377

Overview

Synonyms ADP glucose receptor ,ADP-glucose receptor,ADPG R,ADPG-R,ADPGR ,BDPLT8,G protein coupled receptor SP1999,Gi coupled ADP receptor HORK 3,Gi coupled ADP receptor HORK3,HORK 3,HORK3,P2RY 12,P2RY12,P2T(AC),P2Y 12,P2Y purinoceptor 12,P2Y(12)R,P2Y(AC),P2Y(ADP),P2Y(cyc),P2Y12,P2Y12 platelet ADP receptor,P2Y12,Platelet ADP receptor ,Purinergic receptor P2RY12,Purinergic receptor P2Y G protein coupled 12,Purinergic receptor P2Y12,Putative G protein coupled receptor ,SP 1999,SP1999
Swissprot Q9H244
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human P2RY12
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

 

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