P4HA1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63429

Overview

Synonyms 2-oxoglutarate-4-dioxygenase subunit alpha-1,4-hydroxylase,alpha I subunit,4-PH alpha-1,P4HA,P4HA1,P4HA1,Procollagen-proline,Procollagen-proline,2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase),alpha polypeptide I,Prolyl 4-hydroxylase subunit alpha-1
Swissprot P13674
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human P4HA1
Application WB
Recommended dilution WB 1:1000 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

 

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