PAICS Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15282

Overview

Synonyms ADE2,ADE2H1,AIR carboxylase,AIRC,DKFZp781N1372,MGC1343,MGC5024,Multifunctional protein ADE2,Multifunctional protein ADE2H1,Paics,PAIS,Phosphoribosylaminoimidazole carboxylase,Phosphoribosylaminoimidazole carboxylase,phosphoribosylaminoimidazole succinocarboxamide synthetase,PUR6,SAICAR synthetase
Swissprot P22234
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human PAICS
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.6mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

 

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