PARD6A Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15820

Overview

Synonyms 0710008C04Rik,2610010A15Rik,Par 6 partitioning defective 6 C elegans homolog alpha,Par 6 partitioning defective 6 homolog alpha,Par 6 partitioning defective 6 homolog alpha C elegans,PAR 6A,PAR-6 alpha,PAR-6,par-6 family cell polarity regulator alpha,PAR-6A,PAR6,PAR6A,PAR6alpha,PAR6C,Pard6a,Partitioning defective 6 homolog alpha,partitioning-defective protein 6,partitioning-defective protein 6, C. elegans,homolog of,alpha,Tax interacting protein 40,Tax interaction protein 40,TAX40,TIP 40,TIP-40,TIP40
Swissprot Q9NPB6
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human PARD6A
Application WB,ELISA
Recommended dilution WB 1:500-1:2000
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

 

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