PGLYRP1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-36108

Overview

Synonyms MGC126894,MGC126896,Peptidoglycan recognition protein 1,Peptidoglycan recognition protein,Peptidoglycan recognition protein short,PGLYRP,PGLYRP1,PGRP,PGRP S,PGRP-S,PGRP1,PHRP,short,SBBI68,TAG7,TNF superfamily,member 3 (LTB)-like (peptidoglycan recognition protein),TNFSF 3L,TNFSF3L,UNQ639/PRO1269
Swissprot O75594
Source Rabbit
Reactivity Human
Immunogen Synthesized peptide derived from the Internal region of human PGLYRP1.
Application WB,ELISA
Recommended dilution WB 1:500-1:2000, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-Iå and PGRP-I∫ are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors.

 

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