PHKA1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16708

Overview

Synonyms 5330411D17,9830108K24Rik,kinase PHKA1,KPB1,KPB1,MGC132604,Pcyt1b,PHKA,PHKA1,Phosphorylase b kinase regulatory subunit alpha,Phosphorylase b kinase regulatory subunit alpha,skeletal muscle isoform,Phosphorylase kinase alpha M subunit,phosphorylase kinase,alpha 1 (muscle),RP23 210E20.1,skeletal muscle isoform
Swissprot P46020
Source Rabbit
Reactivity Human,Rat
Immunogen Synthetic peptide of human PHKA1
Application WB,IHC,ELISA
Recommended dilution WB 1:200-1:1000, IHC 1:25-1:100
Concentration 0.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. 

 

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