PLAUR Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-62872

Overview

Synonyms CD 87,CD87,CD87 antigen,MO 3,MO3,Monocyte activation antigen Mo3,Plasminogen activator receptor urokinase,Plasminogen activator urokinase receptor,PLAUR,U PAR,u plasminogen activator receptor,U-PAR,u-plasminogen activator receptor form 2,UPA receptor,uPAR,UPAR,Urinary plasminogen activator receptor,URKR,Urokinase plasminogen activator receptor,Urokinase plasminogen activator surface receptor,urokinase-type plasminogen activator (uPA) receptor
Swissprot Q03405
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human PLAUR
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

 

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