PLXNA4 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16722

Overview

Synonyms FAYV2820,KIAA1550,PLEXA4,Plexin-A4,PlexinA4,PLXA4,plxna4,PLXNA4A,PLXNA4B,PRO34003,UNQ2820/PRO34003
Swissprot Q9HCM2
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human PLXNA4
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.6mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

 

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