PON2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64910

Overview

Synonyms A esterase 2 ,A-esterase 2,Aromatic esterase 2,Paraoxonase 2,Paraoxonase nirs,PON 2,PON2,PON2,Serum aryldialkylphosphatase 2,Serum paraoxonase/arylesterase 2
Swissprot Q15165
Source Rabbit
Reactivity Human,Rat
Immunogen Recombinant protein of human PON2
Application IHC
Recommended dilution IHC 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

 

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