Overview
| Synonyms | Amidophosphoribosyltransferase [Precursor],Amidophosphoribosyltransferase,ATase,Glutamine phosphoribosylpyrophosphatate amidotransferase,Glutamine phosphoribosylpyrophosphate amidotransferase,Glutamine PRPP amidotransferase,GPAT,Phosphoribosyl pyrophosphate amidotransferase,Ppat,PRAT,PUR1 |
| Swissprot | Q06203 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human PPAT |
| Application | WB,IHC,ELISA |
| Recommended dilution | WB 1:500-1:2000, IHC 1:100-1:300 |
| Concentration | 0.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | |
| Tissue specificity | |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. |
