Overview
Synonyms | Amidophosphoribosyltransferase [Precursor],Amidophosphoribosyltransferase,ATase,Glutamine phosphoribosylpyrophosphatate amidotransferase,Glutamine phosphoribosylpyrophosphate amidotransferase,Glutamine PRPP amidotransferase,GPAT,Phosphoribosyl pyrophosphate amidotransferase,Ppat,PRAT,PUR1 |
Swissprot | Q06203 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human PPAT |
Application | WB,IHC,ELISA |
Recommended dilution | WB 1:500-1:2000, IHC 1:100-1:300 |
Concentration | 0.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | |
Tissue specificity | |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. |