PPM1F Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16729

Overview

Synonyms Ca(2+)/calmodulin-dependent protein kinase phosphatase,CaM-kinase phosphatase,CAMKP,CaMKPase,FEM 2,hFEM-2,KIAA0015,Partner of PIX 2,POPX2,PP2C phosphatase,Ppm1f,PPM1F,Protein fem-2 homolog,Protein phosphatase 1F (PP2C domain containing),Protein phosphatase 1F,Protein phosphatase Mg2+/Mn2+ dependent 1F
Swissprot P49593
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human PPM1F
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.8mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. 

 

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