PPP2R1B Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-32639

Overview

Synonyms 2AAB,beta isoform of regulatory subunit A,protein phosphatase 2,PP2A A beta,PP2A subunit A isoform PR65-beta,PP2A subunit A isoform R1-beta,PP2A,subunit A,PR65 beta isoform,PP2A,subunit A,R1 beta isoform,PPP2R1B,PPP4R1,PR65B,protein phosphatase 2 (formerly 2A),regulatory subunit A (PR 65),beta isoform,protein phosphatase 2 (formerly 2A),regulatory subunit A,beta isoform,Protein phosphatase 2,regulatory subunit A,beta,Protein phosphatase 2,structural/regulatory subunit A,beta,protein phosphatase 2,structural/regulatory subunit A,beta isoform,serine/threonine protein phosphatase 2A 65 kDa regulatory subunit A,beta isoform,serine/threonine protein phosphatase 2A,65 kDa regulatory subunit A,beta isoform,Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Swissprot P30154
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the C-terminal region of human PP2A-Aβ
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ICC 1:200-1:1000, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.

 

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