PRDX2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60500

Overview

Synonyms Epididymis secretory sperm binding protein Li 2a,HEL S 2a,MGC4104,Natural killer cell enhancing factor B,Natural killer cell-enhancing factor B,Natural Killer Enhancing Factor B,NKEF B,NKEF-B,NKEFB,Peroxiredoxin-2,PRDX 2,PRDX2,PRDX2,PrP,PRX2,PRXII,PTX1,TDPX1,Thiol Specific Antioxidant 1,Thiol specific antioxidant protein,Thiol-specific antioxidant protein,Thioredoxin Dependent Peroxide Reductase 1,Thioredoxin peroxidase 1,Thioredoxin-dependent peroxide reductase 1,Torin,TPX1,TSA
Swissprot P32119
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human PRDX2
Application WB,IF
Recommended dilution WB 1:500 - 1:2000 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

 

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