PSMA3 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60280

Overview

Synonyms HC8,Macropain subunit C8,MGC12306,MGC32631,Multicatalytic endopeptidase complex subunit C8,Proteasome (prosome macropain) subunit alpha type 3,Proteasome alpha 3 subunit,Proteasome component C8,Proteasome subunit alpha type 3,Proteasome subunit alpha type-3,Proteasome subunit C8,PSA3,PSC8,psmA3
Swissprot P25788
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human PSMA3
Application WB,IF
Recommended dilution WB 1:500 - 1:2000 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.

 

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