PSMA4 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64697

Overview

Synonyms HC9 ,HsT17706 ,Macropain subunit C9,MGC111191,MGC12467,MGC24813,Multicatalytic endopeptidase complex subunit C9,Proteasome (prosome macropain) subunit alpha type 4,Proteasome alpha 4 subunit,Proteasome component C9,Proteasome subunit alpha type 4,Proteasome subunit alpha type-4,Proteasome subunit HC9,Proteasome subunit L,PSA4,PSC9 ,PSMA 4,psmA4
Swissprot P25789
Source Rabbit
Reactivity Human,Mouse,Rat,Monkey
Immunogen Recombinant protein of human PSMA4
Application WB,IHC,IF
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

 

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