PSMB1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60151

Overview

Synonyms FLJ25321,HC5,KIAA1838,Macropain subunit C5,Multicatalytic endopeptidase complex subunit C5,Proteasome (prosome macropain) subunit beta type 1,Proteasome beta 1 subunit,Proteasome component C5,Proteasome gamma chain,Proteasome subunit beta type 1,Proteasome subunit beta type-1,Proteasome subunit HC5,PSB1,PSC5,PSMB 1,PSMB1
Swissprot P20618
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human PSMB1
Application WB,IHC,IF
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.

 

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