PSMB2 Polyclonal Antibody
|Synonyms||HC7 I,Macropain subunit C7 I,Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7 1 ,Multicatalytic endopeptidase complex subunit C7 I ,Multicatalytic endopeptidase complex subunit C7-I,Proteasome (prosome, macropain) subunit beta type 2,Proteasome beta 2 subunit ,Proteasome component C7 I,Proteasome component C7-I,Proteasome subunit beta type-2,PSB2,Psmb2|
|Immunogen||Recombinant protein of human PSMB2|
|Recommended dilution||WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200|
|Storage instructions||Store at -20℃. Avoid freeze / thaw cycles. |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
|Background||The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.|