PSMB2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64757

Overview

Synonyms HC7 I,Macropain subunit C7 I,Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7 1 ,Multicatalytic endopeptidase complex subunit C7 I ,Multicatalytic endopeptidase complex subunit C7-I,Proteasome (prosome, macropain) subunit beta type 2,Proteasome beta 2 subunit ,Proteasome component C7 I,Proteasome component C7-I,Proteasome subunit beta type-2,PSB2,Psmb2
Swissprot P49721
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human PSMB2
Application WB,IHC,IF
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage buffer
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

 

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