PSMB5 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60532

Overview

Synonyms DKFZp459C139,EC 3.4.25.1,LMPX,Macropain epsilon chain,MB1,MGC104214,MGC118075,MGC134464,Multicatalytic endopeptidase complex epsilon chain,Proteasome (prosome, macropain) subunit, beta type, 5,Proteasome beta 5 subunit,Proteasome catalytic subunit 3,Proteasome chain 6,Proteasome epsilon chain,Proteasome subunit beta type-5,Proteasome subunit MB1,Proteasome subunit X,Proteasome subunit, beta type, 5,Proteasome subunit, beta-5,PSB5,PSMB5,PSX large multifunctional protease X,X
Swissprot P28074
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human PSMB5
Application WB,IHC,IF
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.

 

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