PSMC2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15216

Overview

Synonyms 26S protease complex,26S protease regulatory subunit 7,26S proteasome AAA-ATPase subunit RPT1,mammalian suppressor of sgv-1 of yeast,MSS1,Nbla10058,protease 26S subunit 7,proteasome 26S ATPase subunit 2,Proteasome 26S subunit ATPase 2,Proteasome 26S subunit ATPase 2,Protein MSS1,PRS7,PSMC2,putative protein product of Nbla10058,S7
Swissprot P35998
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human PSMC2
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity.

 

You recently viewed

Clear recently viewed
Print Friendly and PDF