PTP4A2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-65270


Synonyms BM 008,EC,HH 13,HH13,HH7 2,HU PP 1,HUPP 1,HUPP1,OV 1,OV1,phosphatase of regenerating liver 2,PRL 2,PRL2,Protein tyrosine phosphatase 4a2,protein tyrosine phosphatase IVA,protein tyrosine phosphatase IVA2,Protein tyrosine phosphatase of regenerating liver 2,protein tyrosine phosphatase type IVA 2,Protein tyrosine phosphatase type IVA member 2 isoform 1,protein tyrosine phosphatase type IVA,member 2,PTP (CAAXII),ptp IV1a,ptp IV1b,PTP4A,PTPCAAX2,TP4A2
Swissprot Q12974
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human PTP4A2
Application WB
Recommended dilution WB 1:200 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal


Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.


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