PTPRT Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16046

Overview

Synonyms Protein tyrosine phosphatase receptor type T,PTPRT,PTPRT,R PTP T,R-PTP-T,Receptor protein tyrosine phosphatase,Receptor-type tyrosine-protein phosphatase rho,Receptor-type tyrosine-protein phosphatase T,RPTP-rho,RPTPmam4,RPTPrho
Swissprot O14522
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human PTPRT
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

 

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