RAB13 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63441

Overview

Synonyms Cell growth-inhibiting gene 4 protein,GIG4,Growth inhibiting gene 4 protein,RAB13,RAB13 member RAS oncogene family,RAB13,RAS associated protein RAB13,Ras related protein Rab13,Ras-related protein Rab-13
Swissprot P51153
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human RAB13
Application WB
Recommended dilution WB 1:1000 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.

 

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