RACGAP1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-32715

Overview

Synonyms CYK4,GAP,Gap1,GTPase activating protein,HsCYK-4,ID GAP,KIAA1478,Male germ cell RacGap,MgcRacGAP,Protein CYK4 homolg,Protein CYK4 homolog,Rac GTPase activating protein 1,Rac GTPase-activating protein 1,RACGAP 1,Racgap1,RGAP1
Swissprot Q9H0H5
Source Rabbit
Reactivity Human,Mouse,Rat,Monkey
Immunogen Synthesized peptide derived from human Rac GAP1 around the non-phosphorylation site of Ser387.
Application WB,IHC-p,IF,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.

 

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