RAMP2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60830

Overview

Synonyms Calcitonin receptor like receptor activity modifying protein 2,Calcitonin-receptor-like receptor activity-modifying protein 2,CRLR activity modifying protein 2,CRLR activity-modifying protein 2,OTTMUSP00000002615,OTTMUSP00000037624,RAMP2,RAMP2,Receptor (calcitonin) activity modifying protein 2,Receptor activity modifying protein 2,Receptor activity modifying protein 2 isoform,Receptor activity-modifying protein 2,RP23-281C18.6
Swissprot O60895
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human RAMP2
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

 

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