RCHY1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14297

Overview

Synonyms Androgen receptor N terminal interacting protein,Androgen receptor N-terminal-interacting protein,ARNIP,CH-rich-interacting match with PLAG1,CHIMP,E3 ubiquitin-protein ligase Pirh2,hARNIP,hPirh2,p53 induced protein with a RING H2 domain,p53-induced RING-H2 protein,PIRH2E,PIRH2F,PRO1996,RCHY1,Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase,RING finger and CHY zinc finger domain-containing protein 1,RING finger protein 199,RNF199,ZCHY,ZFP 363,zinc finger CHY type,Zinc finger protein 363,ZN363,ZNF363
Swissprot Q96PM5
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human RCHY1
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

 

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