RNF181 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64997

Overview

Synonyms 1700047F16Rik,2500002L14Rik,6230415N01Rik,C77350,E3 ubiquitin protein ligase RNF181,HSPC238,LOC51255,MGC103058,MGC94464,OTTHUMP00000209531,OTTHUMP00000209532,RING finger protein 181,RN181,RNF181
Swissprot Q9P0P0
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human RNF181
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background RNF181, also named as HSPC238, is a 153 amino acid protein, which belongs to the RNF181 family. RNF181 is widely expressed, with highest levels in liver and heart and lowest levels in brain and skeletal muscle. RNF181 as a E3 ubiquitin-protein ligase, accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Western blot analysis detected RNF181 protein in human platelets as a 36-kD dimer and an 18-kD monomer.

 

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