S100A1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-36017

Overview

Synonyms Bpb,NEF,Protein S100-A1,S-100 protein alpha chain,S-100 protein subunit alpha,S100 alpha,S100 beta,S100 calcium binding protein A1,S100 calcium binding protein B,S100 calcium-binding protein A1,S100 protein alpha polypeptide,S100A,s100a1,S100B,S100beta,S10A1
Swissprot P23297
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant Protein
Application WB,IHC-p
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

 

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