S100A7 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-62206

Overview

Synonyms HID 5,Protein S100 A7,Protein S100-A7,PSOR 1,PSOR1,Psoriasin 1,Psoriasin,Psoriasin1,S100 Calcium binding protein A7,S100 calcium-binding protein A7,S100A7,S100A7c,S10A7
Swissprot P31151
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human S100A7
Application IHC
Recommended dilution IHC 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

 

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