SCN5A Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16051

Overview

Synonyms Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit,CDCD2,CMD1E,CMPD2,HB1,HB2,HBBD,HH1,ICCD,IVF,LQT3,PFHB1,Scn5a (gene name),Scn5a,SCN5A,Sodium channel protein cardiac muscle alpha subunit,Sodium channel protein cardiac muscle subunit alpha,Sodium channel protein type 5 subunit alpha,Sodium channel protein type V alpha subunit,Sodium channel protein type V subunit alpha,SSS1,VF1,Voltage gated sodium channel alpha subunit Nav1.5,Voltage-gated sodium channel subunit alpha Nav1.5
Swissprot Q14524
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human SCN5A
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.

 

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