SERPINA7 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-17083

Overview

Synonyms Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7,Serpin A7,Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7,Serpin peptidase inhibitor,clade A,member 7,Serpina7,T4 binding globulin,TBG,TBG,serum,THBG,Thyroxin binding globulin,Thyroxine binding globulin,Thyroxine-binding globulin,Thyroxine-binding globulin od serum
Swissprot P05543
Source Rabbit
Reactivity Human
Immunogen Full length fusion protein
Application IHC,ELISA
Recommended dilution IHC 1:25-100, ELISA 1:2000-5000
Concentration 0.7mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

 

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