SETD2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14627

Overview

Synonyms EC 2.1.1.43,FLJ16420,FLJ22472,FLJ23184,FLJ45883,HBP231,HIF 1,HIF-1,HIF1,HIP-1,Histone lysine N methyltransferase SETD2,Histone-lysine N-methyltransferase SETD2,hSET2,HSPC069,Huntingtin interacting protein 1,Huntingtin interacting protein,Huntingtin interacting protein B,Huntingtin interacting protein HYPB,Huntingtin yeast partner B,Huntingtin-binding protein,231-KD,Huntingtin-interacting protein 1,Huntingtin-interacting protein B,HYPB,KIAA1732,KMT3A,Lysine N methyltransferase 3A,Lysine N-methyltransferase 3A,p231HBP,SET domain containing 2,SET domain-containing protein 2,SET2,SETD2,SETD2
Swissprot Q9BYW2
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human SETD2
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

 

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