SHMT2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60257

Overview

Synonyms Epididymis secretory sperm binding protein Li 51e,GLY A+,GLYA,glycine auxotroph A,human complement for hamster,Glycine hydroxymethyltransferase,GLYM,HEL S 51e,mitochondrial,Serine hydroxymethyltransferase 2 (mitochondrial),Serine hydroxymethyltransferase,Serine hydroxymethyltransferase mitochondrial,Serine methylase,SHMT 2,SHMT,SHMT2
Swissprot P34897
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human SHMT2
Application WB,IHC,IF
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

 

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