SIGLEC5 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-33540

Overview

Synonyms CD170,CD170 antigen,CD33 antigen-like 2,CD33L2,mSiglec-F,OB-binding protein 2,OB-BP2,OBBP2,Obesity-binding protein 2,Sialic acid binding Ig-like lectin 5,Sialic acid binding immunoglobulin-like lectin 5,Sialic acid-binding Ig-like lectin 5,Sialic acid-binding Ig-like lectin F,SIGL5,Siglec-5,Siglec-F variant,Siglec5,Siglecf
Swissprot O15389
Source Rabbit
Reactivity Human
Immunogen Synthesized peptide derived from the Internal region of human Siglec-5/14.
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

 

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