SIRT5 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15844

Overview

Synonyms NAD dependent deacetylase sirtuin 5,NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial,NAD dependent protein deacylase sirtuin 5 mitochondrial,NAD-dependent protein deacylase sirtuin-5,mitochondrial,Regulatory protein SIR2 homolog 5,Silent mating type information regulation 2 S.cerevisiae homolog 5,Sir2 like 5,SIR2-like protein 5,SIR2L5,SIR5,Sirt5,Sirtuin 5,Sirtuin type 5
Swissprot Q9NXA8
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human SIRT5
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.

 

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