SIX6 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-32903

Overview

Synonyms Homeobox protein SIX6,Homeodomain protein OPTX2,MCOPCT 2,MCOPCT2,Optic homeobox 2,OPTX 2,OPTX2,Sine oculis homeobox homolog 6,SIX 6,Six 9,SIX homeobox 6,Six6,SIX6,Six9
Swissprot O95475
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of human Six3/6
Application WB,IF,ELISA
Recommended dilution WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:20000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).SIX6 (SIX Homeobox 6) is a Protein Coding gene. Diseases associated with SIX6 include Optic Disc Anomalies With Retinal And/Or Macular Dystrophy and Six6-Related Eye Disorders. Among its related pathways are Ectoderm Differentiation. GO annotations related to this gene include transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is SIX3.

 

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