SLC6A5 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63576

Overview

Synonyms Glycine transporter,Glycine transporter type 2,GlyT-2,GlyT2,NET1,SC6A5,SC6AC5,Slc6a5,SLC6A5 solute carrier family 6 neurotransmitter transporter, glycine member 5,Slc6a9,Sodium and chloride dependent glycine transporter 2,Sodium- and chloride-dependent glycine transporter 2,Solute carrier family 6 member 5,Solute carrier family 6 neurotransmitter transporter glycine member 5
Swissprot Q9Y345
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human SLC6A5
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene.

 

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