SMARCE1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64579

Overview

Synonyms BAF57,BRG1 associated factor 57,BRG1-associated factor 57,Chromatin remodeling complex BRG1 associated factor 57,FLJ35648,SMARCE 1,SMARCE1,SMCE1,SWI/SNF related matrix associated actin dependent regulator of chromatin e1,SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Swissprot Q969G3
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human SMARCE1
Application WB,IF,IP
Recommended dilution WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:20 - 1:50
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

 

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