SOCS6 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10604


Synonyms CIS-4,CIS4,Cish4,Cytokine inducible SH2 protein 4,Cytokine-inducible SH2 protein 4,HSPC060,SOCS-4,SOCS-6,SOCS4,Socs6,SOCS6,SSI4,STAI4,STAT induced STAT inhibitor 4,STAT4,STATI4,Suppressor of cytokine signaling 4,Suppressor of cytokine signaling 6
Swissprot O14544
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human SOCS6
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.3mg/mL
Clonality Polyclonal


Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. 


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