SPDEF Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64933

Overview

Synonyms bA375E1.3,PDEF,Prostate derived Ets factor,PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR,Prostate epithelium-specific Ets transcription factor,Prostate specific Ets,Prostate-derived Ets factor,Prostate-specific Ets,PSE,RP11-375E1__A.3,SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR,SAM pointed domain-containing Ets transcription factor,Spdef,SPDEF
Swissprot O95238
Source Rabbit
Reactivity Human,Rat
Immunogen Recombinant protein of human SPDEF
Application WB
Recommended dilution WB 1:500 - 1:1000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

 

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